{"created":"2023-05-15T11:49:35.500552+00:00","id":385,"links":{},"metadata":{"_buckets":{"deposit":"cb439512-ae39-4f32-9267-822fec60279b"},"_deposit":{"created_by":22,"id":"385","owners":[22],"pid":{"revision_id":0,"type":"depid","value":"385"},"status":"published"},"_oai":{"id":"oai:swu.repo.nii.ac.jp:00000385","sets":["107:282:106"]},"author_link":["875","874","873","878","879","877","872","876"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"914","bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"学苑"},{"bibliographic_title":"Gakuen","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　　Human serum albumin（HSA）is an abundant plasma protein and is modified by glucose in plasma. The incubation of HSA with glucose at 37℃ for four weeks resulted in the formation of carboxymethyllysine in 11 sites of lysine residues of HSA（65, 190 . . .Ⅰ, 199, 233, 313, 378 . . .Ⅱ, 402, 432, 519, 525, 573 . . . Ⅲ）. The same experiments without glucose showed no carboxymethyllysine formation.\n　　Although early studies established that four lysine residues（Lys199, Lys281, Lys439 and Lys525）had been modified by nonenzymatic glycosylation, carboxymethylations of Lys281 and Lys439 were not detected in this experiment. Most carboxymethylation of lysine residues in HSA was located in domain Ⅲ in our study.","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"昭和女子大学近代文化研究所"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1348-0103","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松本, 孝"},{"creatorName":"マツモト, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山倉, 文幸"},{"creatorName":"ヤマクラ, フミユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"重永, 綾子"},{"creatorName":"シゲナガ, アヤコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊藤, 美香"},{"creatorName":"イトウ, ミカ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUMOTO, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAKURA, Fumiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHIGENAGA, Ayako","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ITOH, Mika","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-12-20"}],"displaytype":"detail","filename":"01学苑12月松本先生他.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"01学苑12月松本先生他","url":"https://swu.repo.nii.ac.jp/record/385/files/01学苑12月松本先生他.pdf"},"version_id":"a9c94f76-0422-448b-9704-0f34ca9f8e00"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ヒト血清アルブミン","subitem_subject_scheme":"Other"},{"subitem_subject":"HSA","subitem_subject_scheme":"Other"},{"subitem_subject":"糖化反応","subitem_subject_scheme":"Other"},{"subitem_subject":"CML","subitem_subject_scheme":"Other"},{"subitem_subject":"カルボキシメチルリジン","subitem_subject_scheme":"Other"},{"subitem_subject":"human serum albumin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HSA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"glycation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"carboxymethyllysine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"CML","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"〔研究ノート〕ヒト血清アルブミンの糖化反応による カルボキシメチルリジンの生成箇所の同定","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"〔研究ノート〕ヒト血清アルブミンの糖化反応による カルボキシメチルリジンの生成箇所の同定"},{"subitem_title":"Identification of Carboxymethyllysine Forming Sites by Nonenzymatic Glycation of Human Serum Albumin in Vitro","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"22","path":["106"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-12-20"},"publish_date":"2016-12-20","publish_status":"0","recid":"385","relation_version_is_last":true,"title":["〔研究ノート〕ヒト血清アルブミンの糖化反応による カルボキシメチルリジンの生成箇所の同定"],"weko_creator_id":"22","weko_shared_id":-1},"updated":"2023-05-15T14:09:04.014249+00:00"}