{"created":"2023-05-15T11:52:46.733989+00:00","id":4287,"links":{},"metadata":{"_buckets":{"deposit":"c9744cc8-3b7c-457b-8bfb-84b70c4731cc"},"_deposit":{"created_by":4,"id":"4287","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4287"},"status":"published"},"_oai":{"id":"oai:swu.repo.nii.ac.jp:00004287","sets":["107:282:397"]},"author_link":["7687","7688","7693","7694","7691","7692","7690","7689"],"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-12-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"43","bibliographicPageStart":"40","bibliographicVolumeNumber":"794","bibliographic_titles":[{"bibliographic_title":"學苑"},{"bibliographic_title":"GAKUEN","bibliographic_titleLang":"en"}]}]},"item_3_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"哺乳類の骨格筋や脳に多く含まれ,食肉中の機能性成分として注目されているヒスチジン含有ペプチド(カルノシン,アンセリン)の加齢に伴う筋肉含有量の変化を把握する目的で,2,8,18,40,50,60週令のマウスを用いて検討を行った。また,カルノシンを経口投与した影響も検討した。本研究により,マウス骨格筋中カルノシン量は,8週令のマウスに比較し50週令まで増加を示し,60週令では減少する傾向が観察された。また,40週令マウスの骨格筋におけるカルノシン経口投与の影響は観察されなかった。今後さらに週令の高い動物での検討やカルノシン投与量の検討が必要である。","subitem_description_type":"Other"}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Carnosine is a β-alanyl-L-histidine dipeptide and is found in skeletal muscle and nervous tissue at concentrations ranging from 1 to 25mM. The muscle food that has been postulated to be a bioactive food component contains this dipeptide. Some anti-aging effects of carnosine have also been demonstrated at the whole animal level. There is evidence that carnosine concentrations may decline with age in rodents and humans and the carnosine concentration in the muscles of short-lived species appears to be much lower than that in long-lived species. While carnosine has been detected in mouse muscle, very little is known about the changes of carnosine concentration with, age in detail and after intake of carnosine. Therefore, we investigated the age-related change of carnosine concentration in mouse muscle and the effects of carnosine intake. In this study, carnosine concentration in muscle was increased after birth and carnosine concentration in 60-week-old mice was slightly decreased. While the effects after intake of carnosine was not observed. Further studies should be performed to investigate the changes of carnosine concentration in more aged-mice and the effects after intake of carnosine.","subitem_description_type":"Other"}]},"item_3_description_15":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_description":"10","subitem_description_type":"Other"}]},"item_3_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00004722707","subitem_description_type":"Other"}]},"item_3_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"研究ノート","subitem_description_type":"Other"}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00038441","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13480103","subitem_source_identifier_type":"ISSN"}]},"item_3_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"昭和女子大学食物科学科"},{"subitem_text_value":"昭和女子大学生活機構研究科生活科学研究専攻"},{"subitem_text_value":"昭和女子大学生活科学科管理栄養士専攻"},{"subitem_text_value":"昭和女子大学生活機構研究科"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"黒崎, 瑠美子"},{"creatorName":"クロサキ, ルミコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐治, 信子"},{"creatorName":"サジ, ノブコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小林, 加世子"},{"creatorName":"コバヤシ, カヨコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木村, 修一"},{"creatorName":"キムラ, シュウイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KUROSAKI, Rumiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SAJI, Nobuko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KOBAYASHI, Kayoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KIMURA, Shuichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"KJ00004722707.pdf","filesize":[{"value":"375.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00004722707.pdf","url":"https://swu.repo.nii.ac.jp/record/4287/files/KJ00004722707.pdf"},"version_id":"e8818fc8-f76d-491f-b030-fc452d76dfa8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"カルノシン","subitem_subject_scheme":"Other"},{"subitem_subject":"アンセリン","subitem_subject_scheme":"Other"},{"subitem_subject":"骨格筋","subitem_subject_scheme":"Other"},{"subitem_subject":"加齢","subitem_subject_scheme":"Other"},{"subitem_subject":"L-carnosine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"anserine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"skeletal muscle","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aging","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"加齢に伴うマウス骨格筋中L-carnosine含有量の変化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加齢に伴うマウス骨格筋中L-carnosine含有量の変化"},{"subitem_title":"The Age-Related Change of L-Carnosine Concentration on Skeletal Muscle in Mice","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["397"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-02-16"},"publish_date":"2017-02-16","publish_status":"0","recid":"4287","relation_version_is_last":true,"title":["加齢に伴うマウス骨格筋中L-carnosine含有量の変化"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-05-16T18:49:41.022277+00:00"}